The Science Behind Calm & Ready

"We are committed to using premium ingredients that are clinically validated for effectiveness. Our formulations undergo rigorous testing to ensure safety, purity, and performance. This dedication to quality ensures that every product we offer meets the highest standards, giving you the confidence that you are receiving scientifically backed premium nutrition you can trust."

Setting New Standards

We set the bar high by relying on rigorous clinical trials to validate the efficacy of our products. Unlike many wellness companies, we are committed to transparency and scientific validation. When formulating Calm & Ready, we selected the most clinically studied, highly bioavailable form of ashwagandha available.

Deep Dive: KSM-66® Ashwagandha

Our premium relaxation formula is anchored by KSM-66® Ashwagandha, a highly concentrated full-spectrum root extract. It is produced using a proprietary green chemistry extraction process that avoids the use of alcohol or synthetic solvents. This unique method preserves the natural balance of the herb's active compounds, known as withanolides.KSM-66® is extracted exclusively from the roots and is standardized to contain a minimum of 5% withanolides. This guarantees consistent potency in every single serving of Calm & Ready.

Clinical Trials

The efficacy of KSM-66® is backed by over 50 randomized, double-blind, placebo-controlled clinical trials. These studies demonstrate profound, measurable effects on the body's stress response system, cognitive function, and physical performance.

Clinical Trial 1: Stress and Cortisol Reduction

Objective: To evaluate the safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.

Duration: 60 days

Participants: 64 chronically stressed adults

Key parameters studied:

• Serum cortisol levels

• Perceived stress scores (PSS)

• Anxiety and insomnia symptoms

• Depression scores

Expected outcomes: Regulated stress response, lowered cortisol levels, and improved overall mental well-being.

Results: Participants taking 600 mg of KSM-66® daily experienced a 27.9% reduction in serum cortisol levels and a 44.0% reduction in perceived stress scores compared to the placebo group.

Clinical Trial 2: Sleep Quality Enhancement

Objective: To evaluate the effects of ashwagandha extract on sleep quality in healthy adults and those with sleep disturbances.

Duration: 8 to 10 weeks

Participants: 80 adults

Key parameters studied:

• Overall sleep quality

• Sleep efficiency

• Sleep onset latency

• Mental alertness upon waking

Expected outcomes: Enhanced deep sleep, improved sleep architecture, and increased morning alertness without grogginess.

Results: Participants experienced a 72% improvement in overall sleep quality, alongside measurable enhancements in sleep efficiency and a reduction in the time it took to fall asleep.

Clinical Trial 3: Cognitive Function and Focus

Objective: To assess the efficacy of ashwagandha root extract in improving memory and cognitive functions.

Duration: 8 weeks

Participants: 50 adults

Key parameters studied:

• Immediate and general memory

• Executive function

• Sustained attention

• Information-processing speed

Expected outcomes: Cleared mental fog, sharper focus, and better memory retention.

Results: Supplementation led to significant improvements in both immediate and general memory, as well as enhanced executive function and sustained attention.

Clinical Trial 4: Physical Performance and Vitality

Objective: To examine the effect of ashwagandha supplementation on muscle strength, endurance, and recovery.

Duration: 8 weeks

Participants: 57 healthy adults engaging in resistance training

Key parameters studied:

• Muscle strength and size

• Cardiorespiratory endurance (VO₂ max)

• Body fat percentage

• Hormonal equilibrium

Expected outcomes: Increased physical vitality, enhanced endurance, and improved muscle recovery.

Results: Participants demonstrated significantly greater increases in muscle strength and size, alongside a greater reduction in body fat percentage compared to the placebo group. Other studies have shown a 16.4% increase in VO₂ max.

The Balanced Botanicals Standard

At Balanced Botanicals, we are committed to transparency and efficacy. We selected KSM-66® for Calm & Ready because the data speaks for itself. By combining this clinically proven adaptogen with L-Theanine, Magnesium, and our targeted Vitamin Complex, we have created a comprehensive formula designed to support your body's natural resilience.

References

[1] Chandrasekhar, K., Kapoor, J., & Anishetty, S. (2012). A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. *Indian Journal of Psychological Medicine*, 34(3), 255-262.

[2] Langade, D., Kanchi, S., Salve, J., Debnath, K., & Ambegaokar, D. (2019). Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. *Cureus*, 11(9), e5797.

[3] Deshpande, A., Irani, N., Balkrishnan, R., & Benny, I. R. (2020). A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults. *Sleep Medicine*, 72, 28-36.

[4] Choudhary, D., Bhattacharyya, S., & Bose, S. (2017). Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions. *Journal of Dietary Supplements*, 14(6), 599-612.

[5] Wankhede, S., Langade, D., Joshi, K., Sinha, S. R., & Bhattacharyya, S. (2015). Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial. *Journal of the International Society of Sports Nutrition*, 12, 43.

[6] Tiwari, S., Gupta, S. K., & Pathak, A. K. (2021). A double-blind, randomized, placebo-controlled trial on the effect of Ashwagandha (Withania somnifera dunal.) root extract in improving cardiorespiratory endurance and recovery in healthy athletic adults. *Journal of Ethnopharmacology*, 267, 113412.